Research Catalog

The case of the frozen addicts / J. William Langston and Jon Palfreman.

Title
The case of the frozen addicts / J. William Langston and Jon Palfreman.
Author
Langston, J. W. (James William)
Publication
New York : Pantheon Books, [1995], ©1995.

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StatusFormatAccessCall NumberItem Location
TextRequest in advance RC382 .L37 1995Off-site

Details

Additional Authors
Palfreman, Jon.
Description
ix, 309 pages : illustrations; 24 cm
Summary
  • As scientists raced to capitalize on this breakthrough, Dr. Langston struggled to salvage the lives of his frozen patients, for whom L-dopa provided only short-term relief. The solution he found lay in the most daring area of research: fetal-tissue transplants.
  • Dr. Langston determined that this patient and five others had all used the same tainted batch of synthetic heroin, inadvertently laced with a toxin that had destroyed an area of their brains essential to normal movement. This same area, the substantia nigra, slowly deteriorates in Parkinson's disease.
  • In the summer of 1982, hospital emergency rooms in the San Francisco Bay Area were suddenly confronted with mysteriously "frozen" patients - young men and women who, though conscious, could neither move nor speak. Doctors were baffled, until neurologist J. William Langston, recognizing the symptoms of advanced Parkinson's disease, administered L-dopa - the only known effective treatment - and "unfroze" his patient.
  • The astonishing recovery of two of his patients garnered worldwide press coverage, helped overturn federal restrictions on fetal-tissue research, and offered hope to millions suffering from Parkinson's, Alzheimer's, and other degenerative brain disorders.
Subjects
Genre/Form
Case Reports.
Note
  • Includes index.
ISBN
0679424652
LCCN
94043202
Owning Institutions
Columbia University Libraries