Research Catalog

Title

Dynamics of cancer : incidence, inheritance, and evolution / Steven A. Frank.

Author

Frank, Steven A., 1957-

Publication

Princeton, N.J. : Princeton University Press, [2007], ©2007.

Items in the Library & Off-site

Details

Description

xi, 378 pages : illustrations; 25 cm.

Summary

"This is the only book that presents a full analysis of the age of cancer onset. It is a superb teaching tool and a rich source of ideas for new and experienced researchers. For cancer biologists, population geneticists, evolutionary biologists, and demographers interested in aging, this book provides new insight into disease progression, the inheritance of predisposition to disease, and the evolutionary processes that have shaped organismal design."--BOOK JACKET.

Series Statement

Princeton series in evolutionary biology

Uniform Title

Princeton series in evolutionary biology.

Subjects

• Stem Cells
• Mutagenesis
• Genetic Predisposition to Disease
• Gene Expression Regulation, Neoplastic
• Age of Onset
• Neoplasms > etiology
• Cancer > Epidemiology
• Cancer > Genetic aspects
• Cancer > Age factors
• Carcinogenesis

Bibliography (note)

• Includes bibliographical references (p. [335]-359) and indexes.

Contents

1. Introduction -- 2. Age of cancer incidence -- 3. Multistage progression -- 4. History of theories -- 5. Progression dynamics -- 6. Theory I -- 7. Theory II -- 8. Genetics of progression -- 9. Carcinogens -- 10. Aging -- 11. Inheritance -- 12. Stem cells : tissue renewal -- 13. Stem cells : population genetics -- 14. Cell lineage history -- 15. Conclusions -- App. Incidence.

ISBN

• 9780691133652 (cloth : alk. paper)
• 0691133654 (cloth : alk. paper)
• 9780691133669 (pbk. : alk. paper)
• 0691133662 (pbk. : alk. paper)

LCCN

2007007855

OCLC

• ocm85498596
• 85498596
• SCSB-5353819

Owning Institutions

Columbia University Libraries